Allergic bronchopulmonary aspergillosis presenting with cough variant asthma with spontaneous remission

Allergic bronchopulmonary aspergillosis presenting as chronic cough in an elderly woman without previously documented asthma.

A nonsmoking woman in her mid-70s presents to the allergist for consultation of a chronic cough of almost 3-years' duration without a specific diagnosis as to etiology in spite of numerous diagnostic tests and therapeutic trials. This is a case report from a specialist point of view that includes a comprehensive review of her clinical course pre- and postconsultation along with a brief but pert...

Case report: allergic bronchopulmonary aspergillosis in asthma.

Allergic bronchopulmonary aspergillosis treated with itraconazole.

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Allergic bronchopulmonary aspergillosis treated successfully with omalizumab.

Allergic bronchopulmonary aspergillosis (ABPA) is caused by a hypersensitivity response of type 2 T helper (Th2) lymphocytes to antigens, mostly Aspergillus fumigatus (A. fumigatus).1 This abnormal host response to A. fumigatus in a subset of patients with asthma or cystic fibrosis (CF) is likely due to genetic susceptibility that predisposes patients to the risk of developing ABPA. This is cha...

Aspergillus antigens associated with allergic bronchopulmonary aspergillosis.

Among the molds causing allergy, Aspergillus fumigatus (Af) constituted a major species present both indoors and outdoors. The antigens both secreted and bound to hyphae and conidia have been isolated for immunodiagnosis of allergic aspergillosis. The crude extracts have been used to demonstrate IgE antibody in vitro and for skin testing. The crude extracts contain many antigenic and non-antige...